ctDNA and residual cancer burden after neoadjuvant systemic therapy are independently prognostic in triple-negative breast cancer patients
The effects of omission of radiotherapy after surgery on local or distal recurrence and survival in women with low-risk, hormone receptor–positive early breast cancer
Enrollment of patients with HER2+ metastatic breast cancer and PIK3CA mutation has been started at IEO, to evaluate the addition of alpelisib to current therapies
Olaparib significantly prolonged progression-free survival compared to chemotherapy, particularly in first line patients.
This multicentric machine learning model improves performance of local models in predicting response to neoadjuvant chemotherapy in triple-negative breast cancer.
Foundation’s experts and data in key educational sessions to share knowledge on the role of neoadjuvant therapy and imaging mass cytometry in breast cancer
Lead by Michelangelo Foundation and Gianni Bonadonna Foundation’s experts, a review published on Nature Reviews – Clinical Oncology highlights the state of the art therapy in triple-negative breast cancer
NA-PHER2 trial, coordinated by Michelangelo Foundation, shows their efficacy as neoadjuvant therapy, with a relevant effect on Ki67
Atezolizumab added to nab-paclitaxel and carboplatin as neoadjuvant therapy did not increase the rate of pathological complete remission, mostly influenced by PD-L1 expression
CDK4/6 inhibition with palbociclib, in combination with fulvestrant, trastuzumab and pertuzumab, triggers sustained senescence: new data from a Michelangelo Foundation study